Chernykh Valentin P.

Chernykh Valentin P., Academician of the National Academy of Sciences of Ukraine, Honorary Rector of National University of Pharmacy, Advisor to the Rector, Doctor of Pharmaceutical Sciences, Doctor of Chemical Sciences, Professor of the Department of Organic Chemistry

Address: 61168, Kharkiv, st. Valentynivska (Blucher), 4

Phone: +3 (8057) 67-93-72

E-mail: orgchem@nuph.edu.ua

Autobiography:

Valentin P. Chernykh was born on January 5, 1940 in the village of Rechitsa Orel region. In 1959 he graduated from Kharkov Medical School, in 1964 – Kharkov Pharmaceutical Institute. In 1967 he defended his thesis for the degree of candidate of pharmaceutical sciences, in 1977 he defended his thesis for the degree of Doctor of Pharmaceutical Sciences, in 1990 became Doctor of Chemical Sciences. In 1997 he became a corresponding member of the NAS of Ukraine, in March 2015 – an academician of the National Academy of Sciences of Ukraine.

Valentin P. Chernykh  has passed the way of postgraduate student (1964-1967), assistant (1967-1971), associate professor (1971-1979), senior research fellow (1974-1976), professor (1979-1985), head of the department of organic chemistry (1985-2015), dean (1971-1976), vice-rector for academic affairs (1976-1980). From 1980 to July 31, 2017, he was rector of National University of Pharmacy. In September 2017 he was elected as honorary rector of National University of Pharmacy, in November – an advisor to the rector.

Social activity:

Valentin P. Chernykh is a member of the Chemical Division of the National Academy of Sciences of Ukraine, a member of the Chemistry and Chemical Technology Section of the Committee on State Prizes in Science and Technology, a member of the Scientific Medical Council of the Ministry of Health of Ukraine, State Pharmacological Center for Registration of Drugs, Member of the Expert Council of the Higher Attestation Commission of Ukraine in the field of organic and pharmaceutical chemistry, editor-in-chief of 17 scientific and practical and scientific journals, Chairman of the Specialized Academic Council of National University of Pharmacy Д 64.605.01, Deputy President of the Ukrainian Pharmaceutical Association, President of the Kharkov Pharmaceutical Association, member of the International Pharmaceutical Association.

Scientific school:

Areas of research: design and synthesis of pharmacologically perspective heterocyclic building blocks. Chemistry of benzo- and thienopyrimidines; spiropyrimidines and spiro-2-oxindoles synthesis using multicomponent domino reactions; study of the synthetic potential of cyclic sulfonamides in multicomponent interactions; condensed synthesis of 4H-pyran, 4H-spiro-pyran, 2H-pyran, 4H-thiopyran and 2-pyridone systems based on 1,3-dicarbonyl compounds and their synthetic analogs.

Scientific achievements: Valentin P. Chernykh is an outstanding scientist, an organic chemist, whose works are recognized by the domestic and world community. He is the author of more than 1300 scientific works, including scientific articles in the field of organic, pharmaceutical, physical, medical chemistry and research on the biological activity of synthesized substances, 27 monographs, 10 textbooks, including the textbook ‘Organic Chemistry’ in 3 books, that in 2000 was awarded the State Prize of Ukraine in the field of science and technology (the textbook was published in Ukrainian, Russian, English), 69 teaching aids, 67 author’s texts of lectures. The second edition of the textbook ‘Organic Chemistry’ (2007, 2008) is the first color edition of the textbook on chemistry in Ukraine. In 2014, textbooks ‘Organic Chemistry’ (2007, 2008) and ‘Clinical Pharmacy’ (2013) received the stamp of the Ministry of Health of Ukraine ‘National Textbook’. V.P. Chernykh has created a powerful scientific school that successfully solves theoretical and applied problems in the field of organic synthesis, physical chemistry and pharmacy. Scientist has prepared more than 60 doctors and candidates of sciences. Now under his supervision one doctoral and one candidate’s thesis is being carried out.

Novelty and relevance of scientific research of V.P. Chernykh confirm 126 patents and 341 copyright certificates (among which 119 – on the methods of obtaining BAS and study the pharmacological effect of synthesized substances).

V.P. Chernykh is the author and co-author of 16 original medications. Developed methodology of designing and synthesizing of BAS allowed to synthesize several medicinal substances and develop new medicines on their basis: hypoglycemic medicine ‘Glysulfazid’, antidiabetic ‘Diakamf’, hemostatic ‘Succiphenate’, analgesic ‘Analben’, anti-inflammatory ‘Prolidoxid’ , antiseptic ‘Peronix’, β-adrenoblocker ‘Cardacet’, membranoprotector ‘Melina’, analgesic ‘Valkofen’, analgesic ‘Paravit’, hepatoprotector ‘Piflamin’, ‘Oksaglyukamin’ and others, hold the development of analytical documents, technical regulations and other components of the registration dossier for their industrial production.

Tutorials:

  1. Черних В.П., Зіменковський Б.С., Гриценко І.С. Органічна хімія: Підруч. для студ. вищ. навч. закл. / За заг. ред. проф. В.П. Черних. — 3-тє вид. випр. і доп. — Х.: Вид-во. НФаУ; Оригінал, 2017. — 752 с. іл.
  2. Органічна хімія. Тести з поясненнями : навч. посіб. для студ. вищ. навч. закл. / В. П. Черних, Л. А. Шемчук, Т. О. Колеснікова та ін. ; за ред. В. П. Черних. 3-е вид., стереотип.  – Х. : Вид-во НФаУ, 2017. – 460 с.
  3. Органічна хімія. Стислий курс : навч. посіб. для студ. вищ. навч. закл. / В. П. Черних, Л. А. Шемчук ; за ред. В. П. Черних. – Х. : Вид-во НФаУ, 2016. – 424 с.
  4. Органічна хімія. Тести з поясненнями: навч. посіб. для студ. вищ. навч. закл. / В. П. Черних, Л. А. Шемчук, Т. О. Колеснікова та ін.; за ред. чл.-кор. НАН України В.П. Черних. – Х.: НФаУ, 2014. – 460 с.
  5. Прикладна ІЧ-спектроскопія: навч. посіб. для студ. вищ. навч. закл. / В.П. Черних, Л.А. Шемчук, С.В. Власов та ін.; за ред. чл.-кор. НАН України В.П. Черних. – Х.: НФаУ, 2014. – 152 с.
  6. Енциклопедичний тлумачний словник фармацевтичних термінів: українсько-латинсько-російсько-англійський: навч. посібник для студ. вищ. навч. закл.; за ред. проф. В.П. Черниха. – Вінниця: Нова Книга, 2014. – 824 с.
  7. «Тестові завдання з органічної хімії для підготовки до Ліцензійного іспиту «Крок-1. Фармація» з поясненнями» (2010 р., укр., рос. та англ. мовами);
  8. Сборник тестов по органической химии / Под редакцией чл.-корр. НАН Украины, проф. Черных В.П. – Х.: Изд-во НФаУ: Золотые страницы, 2005.- 376 с. (проф. Шемчук Л.А. – автор глав 1-20),
  9. От субстанции к лекарству: Учебное пособие/ П.А. Безугый, В.В. Болотов, И.С. Гриценко, С.М. Дроговоз, А.В. Зайченко, И.А. Зупанец, Б.А. Самура, Э.В .Супрун, В.П. Черных, Л.А. Шемчук; Под ред. В.П.Черных. – Харьков: Изд-во НФаУ: Золотые страницы, 2005. – 1244 с.
  10. «Абітурієнту Національного фармацевтичного університету» (2003, 2004)
  11. «Тестові завдання для контролю знань випускників спеціальності «Фармація» (2003)
  12. «Тестові завдання для контролю знань випускників спеціальності «Технологія фармацевтичних препаратів» (2003)
  13. «Абітурієнту Національної фармацевтичної академії України» (2001, 2002)
  14. Збірник тестових завдань з органічної хімії «Ліцензійний іспит. Крок 1. Фармація» (2001–2013)

Teaching aids:

  1. Общий практикум по органической химии: Учебное пособие для студентов вузов III–IV уровней аккредитации /В.П. Черных, И.С. Гриценко, М.О. Лозинский, З.И. Коваленко; Под общ. ред. В.П. Черных. – Х.: Издательство НФАУ; Золотые страницы, 2002. – 592 с.: ил.
  2. Загальний практикум з органічної хімії: Навч. посіб. для студ. вищ. навч. закл. III – IV рівнів акредитації / В. П.Черних, І. С. Гриценко, М.О. Лозинський, З.І. Коваленко; За ред. В. П.Черних. – Х.: Изд-во НФАУ; Золоті сторінки, 2003. – 592 с.; іл.

English textbooks:

  1. Organic chemistry. Tests with explanations: the study manual for students of higher schools. – Kh.: NUPh, 2015. – 456 p.
  2. Chernykh V. P., Shemchuk L. A. Apllied infrared spectroscopy: a manual for students of higher schools / edited by associate-member of the NAS of Ukraine V. P. Chernykh. – Kharkiv: NUPh, 2014. – 152 p.
  3. Chernykh V.P., Shemchuk L.A. Organic chemistry. Short lecture course 1-31 lectures / edited by V.P. Chernykh. – Kharkiv: NPhaU, 2012.
  4. Chernykh V.P., Shemchuk L.A. Organic chemistry. Basic lecture course: The study guide for students of higher schools / Edited by V.P. Chernykh.– 4 ed., rev. and enl.– Kharkiv: NUPh, Original, 2011. – 440 p.
  5. Organic chemistry tests collection: Manual for the students of higher educ. establ. / Under the editorship of V.P. Chernykh. — Kh. National University of Pharmacy, 2008 – 319 p.; 2011 – 319 р.

Monographs:

  • «История кафедры органической химии Национального фармацевтического университета»
  • Кн. 1. Кафедра органической химии в формате двух столетий/ В.П. Черных. – Харьков: Золотые страницы, 2009. – 304 с.
  • Кн. 2. Кафедра органической химии: прошлое и настоящее, традиции и новаторство/ Редкол.: В.П. Черных (председатель) и др.; Сост. Л.А. Шемчук, Т.В. Шпичак, и др. – Харьков: Золотые страницы, 2009. – 904 с.
  • видання серії «Вчені – фармації» В.П. Черных. Полвека в фармации: библиографический указатель/ сост.: Л.А. Шемчук, Т.В. Шпичак, З.Ф. Подстрелова и др. – Харьков: Золотые страницы, 2009. – 544 с.

Articles in specialized foreign scientific journals:

  1. Synthesis and antimicrobial activity of Bis-Derivatives of 3a′, 6a′Dihydro-2’H-Spiro[Indole-3,1′-Pyrrolo[3,4-c]Pyrrole]-2,4′,6′(1H, 3’H, 5’H)-Trione/ R. G. Redkin, E. I. Syumka, L. A. Shemchuk, V. P. Chernykh // Journal of Applied Pharmaceutical Science. – 2017. – Vol. 7 (06), pp. 069-078.
  2. Synthesis of 1-ethyl-1H-2,1-benzothiazine 2,2-dioxide derivatives using cycloalkanecarbaldehydes and evaluation of their antimicrobial activity. D. A. Lega, V. P. Chernykh, L. Zaprutko, A. K. Gzella and L. A. Shemchuk, Chemistry of Heterocyclic Compounds (New York, NY, United States), 2017, 53, 219-229
  3. Peculiarities of 2-amino-3-R-4-aryl-4H-pyranes multicomponent synthesis derived from 1H-2,1-benzothiazin-4(3H)-one 2,2-dioxide / A. Lega, N. Y. Gorobets, V. P. Chernykh, S. V. Shishkina and L. A. Shemchuk // RSC Adv. ‑ 2016, 6, 16087-16099
  4. An efficient, three-component synthesis and molecular structure of derivatives of 2-amino-3-R-6-ethyl-4,6-dihydropyrano[3,2-c][2,1]benzothiazine-5,5-dioxide spirocombined with a 2-oxindole nucleus // Tetrahedron. – 2014. – Vol. 70
  5. Synthesis and molecular structure of spirocyclic 2-oxindole derivatives of 2-amino-4H-pyran condensed with the pyrazolic nucleus // Tetrahedron. 63 (2007)

Articles in specialized scientific journals of Ukraine:

  1. Synthesis of 1,2-benzoxathiine 2,2-dioxide derivatives using aliphatic aldehydes and assessment of their antimicrobial activity / [G. Grygoriv, D. Lega, V. Chernykh, L. Shemchuk et al]. // Journal of Organic and Pharmaceutical Chemistry. – 2017. – Vol. 4. Issue 60. – P. 33–40.
  2. Cycloalkanecarbaldehydes in synthesis of novel 1,2-benzoxathiin4(3H)-on 2,2-dioxide derivatives and study of the antimicrobial activity of synthesized compounds / [G. Grygoriv, D. Lega, V. Chernykh, L. Shemchuk et al]. // Sciencerise. – 2017. – Vol. 6. Issue 10. – P. 4–10.
  3. The study of three-component interaction between 1-ethyl-1Н-2,1-benzothiazin-4(3Н)-one 2,2-dioxide, heterylcarbaldehydes and active methylene nitriles // D. A. Lega, V. P. Chernykh and A. Shemchuk // Journal of Organic and Pharmaceutical Chemistry. – 2016. – Т. 14, №1 (53). С. 6-16.
  4. The use of aliphatic aldehydes in the synthesis of new pyran annulated derivatives of 1H-2,1-benzothiazin-4-one 2,2-dioxide via domino-type interactions. The antimicrobial activity of the compounds synthesized // D. A. Lega, N. I. Filimonova, O. G. Geyderikh, V. P. Chernykh and L. A. Shemchuk // Journal of Organic and Pharmaceutical Chemistry. – 2016. – Т. 14, С. 29-40.
  5. Studying the Grignard reaction of qunazolinone derivatives containing an ester group // ЖОФХ. – 2011. Т. 9. – Вип. 3 (35);
  6. Синтез конденсированных 2’-амино-3’-R-спиро[индол-3,4’-пиран]-2(1Н)-онов // ЖОрХ. – 2008.-Т.44, вып. 12;
  7. Синтез 2-R-3-гидрокси-[1,2,4]триазино[6,1-b]-хиназолин-4,10-дионов // ЖОрХ. – 2006.-Т.42, вып.5;
  8. Превращение диацильных производных антранилогидразида в условиях циклодегидратации // ЖОрХ. – 1999.-Т.35, вып. 2;
  9. Превращение N’-антранилоилгидразидов дикарбоновых кислот: синтез производных хиназолин-4-она // ЖОрХ. – 1998. – Т. 34. – Вып. 4;
  10. Кинетика гидразинолиза N-(арилсульфонамидо)глутаримидов в диметилформамиде. К вопросу о механизме влияния сульфонамидного фрагмента на реакционную способность имидов // ЖОрХ. – 1994. – Т. 30. – Вып. 6.

Disciplines: Organic chemistry, Bioorganic chemistry, Physical and chemical methods of organic compounds studying, Instrumental methods of analysis of organic compounds

Hobby: sport.