A.Y. Bochkarova, О.А. Evtifeyeva, A.V. Glushchenko, V.A. Georgiyants І
STANDARDIZATION OF METHOD OF THE QUANTITATIVE DETERMINATION OF AETHACRIDINI LACTAS IN MEDICINAL FORMS
The validation of the analytical method of determination of quantitative content of aeth-acridini lactas is conducted by the method of iodchlorimetry in the medicinal form of the pharmacy manufacturing at first time. Procedure of validation was carried out under the scheme which is resulted in the State Pharmacopoeia of Ukraine (SPU). The experimental data are not exceeded by the criteria of acceptability of analytical method that determines a fitness and correctness of method to the put tasks in the conditions of pharmacies and laboratories on the analysis of quality. Keywords: aethacridini lactas; validation of the analytical method; method of iodchlorimetry
В. Є. Доброва, С. М. Коваленко, Л. М. Малоштан, К. О. Степанова
Національний фармацевтичний університет
ВАЛІДАЦІЯ БІОАНАЛІТИЧНИХ МЕТОДІВ ДЛЯ ФАРМАКОЛОГІЧНИХ ДОСЛІДЖЕНЬ ЛІКАРСЬКИХ ЗАСОБІВ ЗГІДНО ВИМОГ СТАНДАРТУ ДСТУ ISO/IEC 17025: 2005
The aspects of the validation methods which used in various biological and pharmacological studies was discussed in this paper. Analysis of the existing regulatory framework concerning the conduct of validation showed that, in contrast to the modern production processes and analytical methods for drug quality control, preclinical studies do not have sufficient methodological support for validation to assess their suitability. Given the requirements of the standard ISO/IEC 17025: 2005 approaches to the creation of plans bio-analytical methods validation was proposed. In accordance with these recommendations the validation of a new technique was conducted at the Problem laboratory of the morpho-functional researches. Key words: validation; standards; bioanalytical methods of research; medicine; the measurement uncertainty.
O.B.Posilkina, К. S. Svitlichna
DEVELOPMENT OF ESTIMATION’S FUNCTIONING TOOL OF INTEGRATED SYSTEM OF MANAGEMENT AT PHARMACEUTICAL ENTERPRISES
In the article the estimation’s method of effective functioning of integrated system of management at pharmaceutical enterprises is offered. This method different groups of processes separately and integrated system of management wholly is allowed to estimate. Key words: integrated system of management, processes of pharmaceutical enterprise, effectiveness of functioning.
О. V. Posylkina, Yu. A. Babichenko, Ya. G. Onischenko
THE QUALITY CONTROL OF INCINERATION PROCESS OF NATURAL GAS IN CALDRON SETTING OF PHARMACEUTICAL PRODUCTIONS
The algorithm of calculation of indexes of analysis of combustion products plenitude of natural gas in caldron setting of pharmaceutical productions is developed, the automatic checking system of quality of incineration on the base of gas analyzer, which are series-produced by domestic industry, is developed. Key words: quality; control; pharmaceutical production; setting of receipt of the distilled water; natural gas
Horilyk, В. Hromovyk, S. Tereshchuk
REVIEW OF VIRTUAL LEARNING ENVIRONMENTS AS A PLATFORMS FOR PHARMACEUTICAL EDUCATION
The article made review of 24 software products – virtual learning environments (VLE). Information about their requirements, distribution and use conditions was given. For a detailed analysis of the functional characteristics of five selected VLE (Atutor, Claroline, eFront, Ilias, Moodle) the source software codes were taken from official developers websites and installed on the test computer. VLE eFront and Moodle identified as the most promising and suitable platforms for pharmaceutical education. Key words: virtual learning environment; e-learning; graduate and post-graduate pharmacy studies; eFront; Moodle.
О. V. Posilkina, О. Y. Horbunova
CONSTRUCTION AND STANDARDIZATION OF PROCESS OF LOGISTIC SERVICE OF CUSTOMERS OF INDUSTRIAL PHARMACEUTICAL ENTERPRISES
In the article is grounded actuality of forming and development of logistic service of customers of industrial pharmaceutical enterprises as one of elements of optimization of partner co-operation. The necessity of standardization of treatment of orders is well-proven in the conditions of passing to the international standards of quality. The sequence of subprocesses, functions, operations of process of logistic service of customers of industrial pharmaceutical enterprises is offered. Key words: logistic service; processes approach; partner relations; industrialpharmaceutical enterprise
APLICATION OF MARKETING BALANCED SCORECARD OF PHARMACEUTICAL WHOLESALER
Application of the system of the balanced scorecard for the evaluation of effectiveness of functional direction marketing pharmaceutical wholesale firms is grounded. Strategic aims, their measuring devices, operative aims and measures of achievement, to separate direction of marketing activity of firm are certain. The example of calculation of operative aims realization degree and general potential of marketing of pharmaceutical wholesale enterprise is resulted. Keywords: strategic management; system of the balanced scorecard; marketing; pharmaceutical wholesale firm
V. Iakovlieva, О. N. Kyrychenko
PHARMACOECONOMIC EVALUATION 1 THE INNOVATIVE COMPLEX PREPARATION ! OF VITAMIN B1 IN DIABETIC POLINEYROPATII THERAPY
Pharmacoeconomic analysis diabetic polyneuropathy schemes of therapy with use of vitamins В (Bi; B6) preparations was spent. Pharmacoeconomic expediency of complex preparation Milgamma® application in diabetic polyneuropathy therapy was defined. Keywords: diabetic polyneuropathy; vitamins В (B1; B6) preparations; water- and oil-soluble forms of vitamin B1 preparation; pharmacoeconomic analysis