Journal of organic and pharmaceutical chemistry 2015 Volume 13 Issue 4 (52)

CONTENTS 

THE SYNTHESIS OF 1,5-DIARYL-4-ARYLTHIOPYRROLIDIN-2-ONES BY ARYLSULFЕNYLATION OF STYRYL ACETIC ACID N-ARYLAMIDES
N.M.Tsyzoryk, I.Yu.Danyliuk, A.I.Vaskevych, R.I.Vaskevych, M.V.Vovk

METHYLATION OF POSITION 8 IN THE PYRIDINE MOIETY OF THE N-(BENZYL)-2-HYDROXY-4-OXO-4Н-PYRIDO[1,2-a]PYRIMIDINE-3-CARBOXAMIDE MOLECULE AS AN ATTEMPT TO ENHANCE THEIR ANALGESIC PROPERTIES
I.V.Ukrainets, O.V.Gorokhova, L.V.Sydorenko, S.G.Taran

A CONVENIENT WAY OF 3-FLUORO-1,8-NAPHTHALIMIDE SYNTHESIS
N.F.Fed’ko, V.F.Anikin

TESTING OF A NEW DOCKING SCORING FUNCTION ON THE EXAMPLE OF INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B
V.Yu.Tanchuk, V.O.Tanin

SYNTHESIS AND THE ANTIMICROBIAL ACTIVITY OF 3-(2-METHYL-4-OXO-1,4-DIHYDROQUINOLINE-3-YL)PROPANOIC ACIDS
V.O.Zubkov, T.P.Osolodchenko, N.I.Ruschak, O.L.Kamenetska, O.V.Kiz

THE SYNTHESIS AND ANTICANCER PROPERTIES OF 2-(4-AMINO-5-METHYL-4H-[1,2,4]TRIAZOL-3-YLSULFANYL)-N-(5-R-BENZYLTHIAZOL-2-YL)-ACETAMIDES
Yu.V.Ostapiuk, V.S.Matiychuk, M.D.Obushak

THE SYNTHESIS, REACTIVITY AND THE ANTIMICROBIAL ACTIVITY OF SUBSTITUTED THIENO[2,3-d]PYRIMIDINE-4(3H)-THIO(SELENO)NES
D.O.Kolomieitsev, V.I.Markov, V.O.Astakhina, S.I.Kovalenko, S.A.Varenichenko, O.V.Kharchenko

THE STUDY OF REGULARITIES OF THE STRUCTURE – ANALGESIC ACTIVITY RELATIONSHIP IN A SERIES OF 4-HYDROXY-N-(PYRIDIN-2-YL)-2,2-DIOXO-1H-2λ6,1-BENZOTHIAZINE-3-CARBOXAMIDES
I.V.Ukrainets, L.O.Petrushova, O.V.Gorokhova, O.O.Davydenko

THE COMPLEXING ABILITY OF N-SUBSTITUTED THIOUREA DERIVATIVES AS CHELATING LIGANDS IN THE REACTION WITH PdCl2
Yu.L.Zborovskii, V.V.Orysyk, D.O.Melnychenko, S.I.Orysyk, H.H.Repich, L.V.Garmanchuk, L.I.Palchykovska, V.I.Pekhnyo, M.V.Vovk

5,6-DIHYDRO-[1,2,4]TRIAZOLO[1,5-С]QUINAZOLINES. MESSAGE 1. FEATURES OF INTERACTIONS BETWEEN [2-(3-ARYL-1H-1,2,4-TRIAZOLE-5-YL)PHENYL]AMINES, ALIPHATIC AND AROMATIC ALDEHYDES
S.V.Kholodnyak, K.P.Schabelnyk, O.Yu.Voskoboynik, G.G.Berest, S.I.Kovalenko

The synthesis and evaluation of the bactericidal activity of 4-(4-chloro-1H-imidazol-5-yl)-2-oxo-1,2-dihydropyridin-3-carbonitriles
O.Ya.Mel’nyk, V.O.Chornous, N.D.Yakovychuk, N.V.Mel’nichenko, M.V.Vovk

DEVELOPMENT AND VALIDATION OF THE METHOD FOR DETERMINATION OF RELATED IMPURITIES IN RIBOXIN TABLETS
M.V.Rosada, N.Yu.Bevz, V.A.Georgiyants

The study of retention regularities for the potential drug substances of 1,2,4-triazol-3-ylthioacetic acids and their salts series by the method of HPLC/DAD-MS
B.O.Varynskyi, Ye.G.Knysh, V.V.Parchenko, O.I.Panasenko, A.G.Kaplaushenko