The antifungal activity of ethylacetate-ethanolic (8:2) fractions of Lady’s Bedstraw (Galium verum L.), Galium salicifolium Klok. and Cruciform Bedstraw (Galium cruciata (L.) Scop.) with respect to 10 test strains of Candida fungi: C. albicans ATCC 885/653, C. parapsilosis 488/10, С. yamata (Debariomyces hansenii) 40 b / 3 C. rugosa Sklyar 27, C. tropicalis F-195, C. tropicalis 195, C. utilis (Pichajadinii) CCTM 991, С. intermedia Y-59, C. intermedia ATCC 14439 and C. glabrata 1712 has been studied. The ethylacetate-ethanolic (8:2) fraction of Lady’s Bedstraw revealed the activity in relation to 10 test-cultures used, the Cruciform Bedstraw’s fraction — to 8 test-cultures, the fraction of Galium salicifolium was active in relation to 5 test cultures. The results of the experiment provide a background for creating medicinal forms with the antifungal action on the basis of Galium verum, Galium salicifolium and Galium cruciata ethylacetate-ethanolic fractions.
Key words: Bedstraws, ethylacetate-ethanolic fractions, fungi of the Candida genus, antifungal activity, phenolic compounds, terpenoids
