Almakaieva Liudmyla Grygorivna

Алмакаева Л. Г.Almakaieva Liudmyla Grygorivna – D.Sc. in Pharmacy, senior research scientist, Head of the Research Laboratory of parenteral and oral liquid medicines, Professor of the Quality Management Department.

Address: 4, Blukhera str., Kharkiv, 61168
Tel. / Fax: (0572) 68-56-71
E-mail: parenteral@ukrfa.kharkov.ua
E-mail: Almakaeva@ukr.net

Biography

Almakaieva Liudmyla Grygorivna (born 11.04.1957 in Yelyzavetgradivka, Kirovograd region) – D.Sc. in Pharmacy (2008), senior research scientist (2003), Head of the Research laboratory of parenteral and oral liquid medicines (2011), Professor of the Quality Management Department (2012).

She has graduated from the Ukrainian Open Polytechnic Institute named after I.Z. Sokolov (1983) in specialty “Technology of Basic Organic and Petrochemical Synthesis”, qualification – chemical process engineer.

Liudmyla Grygorivna worked at the State Enterprise “State Scientific Center of Medicines” (SE “SSCM”): senior laboratory assistant, engineer (1979), junior research scientist (1986), research scientist (1994); Head of the Research laboratory of parenteral and oral liquid medicines (1996-2011), Deputy director for Science (2008), part-time – Head of the Research laboratory of parenteral and oral liquid medicines; Acting Director (2010-2011).

Head of the Research laboratory of parenteral and oral liquid medicines of the National University of Pharmacy (2011): professor of the Quality Management Department (2012).

Research directions: technology and standardization of production of parenteral and oral liquid medicines, scientific – methodological approaches based on the medicines’ composition justifications; pharmaceutical development of composition and technology, development of NTD (normative and technical documentation) for the registration of industrial production of medicines; validation of industrial process, formation of quality management systems for the pharmaceutical companies.

Under the supervision of L.G. Almakaieva the following original medicines have been developed – combination infusion medicine “Taurikam” (patent № 38178), cardiovascular agent medicine “Glutakam” (RF patent № 2168989), for the first time injectable dosage form of “Quercetin” (RF patent № 2181051) was developed, etc. Study of the possibility of parenteral agents creation based on insoluble substances of plant (baicalin, luteolin) and synthetic origin is in process with the participation of L.G. Almakaieva. Scientific novelty of the research conducted by L.G. Almakaieva is in the first algorithm for preparation of injectable solutions based on amino acids. Original cardio – vascular and hepatoprotective medicines (Asparkam, Taurikam, Glutakam, Glutargin, Cardioarginin, etc.) were developed on its basis.

Scientific achievements: Liudmyla Grygorivna is the developer of more than 50 medicines registered and put into industrial production. She the co-author of five general articles for State Pharmacopoeia of Ukraine, author of over 150 scientific papers, including one monograph, 22 patents. Since 2007 she is the member of the International Academy of Informatization.

Training of scientific staff (4 Candidates of Sciences):

  1. Shevchenko Iryna Vasylivna, C.Sc. in Pharmacy, specialty 15.00.03 – standardization and organization of drugs production. Dissertation “Development of composition and standardization of the production of injection hypoazotemic medicine based on flavonoids” (June 12, 2002).
  2. Dolia Volodymyr Grygorovych, C.Sc. in Pharmacy, specialty 15.00.03 – standardization and organization of drugs production. Dissertation “Development of methods for the control of mechanical inclusions and their standardization in parenteral medicines” (June 13, 2002).
  3. Naumenok Liudmila Grygorivna, C.Sc. in Pharmacy, specialty 15.00.03 – standardization and organization of drugs production. Dissertation “Development of composition and standardization of the production of injectable anticonvulsant and      antiarrhythmic medicines based on hydantoin derivatives” (July 1, 2004).
  4. Biegunova Nataliia Vlasiivna, C.Sc. in Pharmacy, specialty 15.00.03 – standardization and organization of drugs production. Dissertation “Development of composition and industrial technology standardization of cardio – vascular agents for parenteral use based on salts of aspartic acid” (November 21, 2006).

Awards: Silver medal of theExhibition of Achievements of the National Economy for development of the tests to identify drugs. Liudmyla Grygorivna was awarded the Certificates of Honour of the Ministry of Health of Ukraine, Kharkiv Regional State Administration andjoint organization of employers of medical and microbiological industry of Ukraine for long and dedicated work.

Major works:

  1. К созданию гос Фармакопеи Украины . Стандартизация ле – карственных средств для парентерального применения / Асмолова Н.Н. , Ал- Макаева Л.Г. , Вырова Е.В. , Донштрубова А.Г. , Георгиевский В.П. / / Фарма – ком. – 1999 . – № 5 . – С. 42-48.
  2. Алмакаев Л.Г. Разработка состава и технологии получения нового препарата для инъекций ” Глутакам ” / Алмакаев Л.Г. , Бегунова Н.В. , Алмакаев М.С. / / Вестник фармации . – 2005 . – № 3 (43 ) . – С. 68-72 .
  3. Алмакаев Л.Г. Глутаргин – новое лекарственное средство гепатопротекторного действия / Алмакаев Л.Г. , Харченко О.В. , Фаст Л.Г. / / Актуальные вопросы фармацевтически ческой и медицинской науки и практики : Сб. наук . ст. Запорожского государственного медицинского ун-та . – 2004 . – Т.1 , вып. XV . – С. 383-386 .
  4. Алмакаева Л.Г. Разработка технологи лекарственных форм для парентера – льного применения на основе аргинина гидрохлорида / Алмакаева Л.Г. , Нау – Менок Л.Г. / / Фармаком . – 2006 . – № 1 /2. – С. 140-143 .
  5. Судьба В.Г. К вопросу о калибровке анализаторов светоблокировочного дей- ствия для контроля механических включен в инъекционных растворах / Судьба В.Г. , Алмакаева Л.Г. / / Фармаком . – 2001 . – № 4 . – С. 77-80 .
  6. Производство ампул медицинского назначения. / Будникова Т.Н. , Гульпа В.С. , Шматенко А.П. , Алмакаев Л.Г. / / Фармацевтической . журн. – 2004 . – № 6 . – С. 99-101 .
  7. Алмакаев Л.Г. Технологические аспекты создания инфузионных Лекарственных по – ных средств на основе аминокислот / Алмакаев Л.Г. , Судьба В.Г. / / Фармацевтической . журн. – 2006 . – № 6 . – С. 88-92 .
  8. Разработка методик количественного определения аминокислот в лекарственных препа – ратах методом высокоэффективной жидкостной хроматографии / Харченко О.В. , Алмакаев Л.Г. , Шеин А.Т. , Назарова А.С. / / Фармацевтической . журн. – 2007 . – № 1 . – С. 88-92 .
  9. Алмакаева Л.Г. Обоснование состава и технологии получения препарата ” Глутарсол ” для инфузионной терапии / Алмакаева Л.Г. , Науменок Л.Г. , Ше – вченко И. В. / / Фармаком . – 2007 . – № 2 . – С. 67-71 .
  10. Алмакаев Л.Г. Контроль механических включений в лекарственных средствах для парентерального применения : просмотр КД 42У – 001- 93 / Алмакаев Л.Г. , Судьба В.Г. , Георгиевский В.П. / / Запорожский медицинский журнал. – 2007 . – № 2 ( 41). – С. 124-128 .
  11. Л.Г.Алмакаева , Л.Г. Науменок , Н.В. Бегунова , В.Г. Судьба , М.С. Алмакаев Совершенствование технологии производства кальция хлорида , 10 % раствора для инъекций / / Вестник фармации . – 2013 . – № 3 (75 ) . – С. 8-11 .
  12. Л.Г.Алмакаева , Л.Г. Науменок , Н.В. Бегунова , В.Г. Судьба , М.С. Алмакаев . Разработка состава лекарственного средства на основе мелоксикама / / Вестник фарма -ции . – 2013 . – № 3 (75 ) . – С. 31-35 .

Teaching of disciplines: Certification of products and services.

Hobbies: floristics, cooking, traveling, fishing, mushrooming

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