The Central Scientific-Research Laboratory (CSRL)

koshova1-232x300Adress: 61002, Kharkiv, Melnikova str., 12

Tel.:  +38 (057)706-23-12, +38 (057)706-23-14

Fax:  +38 (057)706-23-12

Mail: cndl@nuph.edu.ua

Head: Koshevaya Elena.

Main aims:

  • design, study, creation and adoption of new medicines
  • training scientists of the highest qualification: candidates and doctors of sciences in “Pharmacology”

In the CSRL we hold pre-clinical studies of medicines from such clinico-pharmacological groups:

  • Nonsteroidal anti-inflammatory drugs and nonopioid analgetics
  • Antiulcer drugs
  • Hepatoprotectors
  • Antioxidants and antihypoxic agents
  • Cardioprotectors
  • Antiallergenic drugs
  • Adaptogen and actoprotectors
  • Hypoglycemic agents
  • Veintonic agents
  • Topical agents (ointments, gel)
  • Wound healing agents
  • Cerebroprotectors
  • Prostatoprotectors
  • Geroprotectors
  • Stressprotectors
  • Hypolipidemic agents
  • agents for treatment diseases of upper airways

Objects for pharmacological studies are:

  • Substances of synthetic, phytochemical and natural origin;
  • Substances and dosage forms of perspective agents;
  • Dosage forms of known pharmacological substances;
  • Known drugs, which are being on the pre-clinical studies at a new indications.

Experimental pharmacological studies include:

  • Investigation of specific pharmacological activity;
  • Investigation of pharmacodynamics.
  • Toxicological research:

– Acute toxicity
– Toxicity under repeated administration (subacute, subchronic and chronic)

  • Investigation of specific toxicity:

– Embryotoxicity (and teratogenicity)
– Gonadotoxicity
– Immunotoxicity
– Sensitizing effect
– Mutagenicity
– Ulcerogenic effect
–  Pyrogen effect
–  Cumulating effect
– Local irritating effect

  • Pharmacological research