This method for evaluation of tolerability when studying drug bioequivalence has been proposed. While its developing a generalized block diagram for carrying out the research in accordance with the requirements of ICH GCP and the algorithm of statistical planning and Read more
This article deals with the analysis of literature and research results in the field of in silico technologies. The information of the main in silico methods is summarized. The main principles of molecular docking, homology modelling method, virtual screening, pharmacophore Read more
On January 25, on the day of St. Tatiana – the patroness of all students -THE PARADE OF NERDS took place. This first and unique event which marks the beginning of a new city tradition was held in the renovated Read more
Ph.D. Dissertations Defense: Korovenkova O.M. (Scientific supervisor D.M., prof. Kosuba R.B.) Kurt-Ahmetova G.S. (Scientific supervisor D.M., prof. Mamchur V.I.) Responsible Chairman of the Specialized Scientific Council prof. Zupanets I.A. Academic Secretary of the Specialized Scientific Council assoc. prof. Saharova Read more
It has been determined that isolation of mianserin from the biological material by acidified acetonitrile (according to I.Szrzedzinski’s method) is more effective for forensic and toxicological examination than isolation by neutral acetone (by V.A.Kartashov’s method) and chloroform. Resolution of the Read more
The research results of the influence of thick extract of Silver birch leaves in the dose of 7 mg/kg and the reference medicine “Canephron® N” in the dose of 20 mg/kg on the functional activity of the kidneys, as well Read more
In the process of pharmacological screening of 3-succinylsubstituted N-phenylanthranilic acids it has been found that these compounds show a high anti-inflammatory, analgetic, diuretic, fungistatic and bacteriostatic activity. The parameters of acute toxicity have been defined for the most active derivatives, Read more
The aim of the research was to develop an experimental model of intestinal dysbiosis induced by diclofenac sodium and to study the effect of probiotic Bifidumbacterin on functional characteristics of the intestine in the reproducible conditions. Animals were divided into Read more
The antifungal activity of ethylacetate-ethanolic (8:2) fractions of Lady’s Bedstraw (Galium verum L.), Galium salicifolium Klok. and Cruciform Bedstraw (Galium cruciata (L.) Scop.) with respect to 10 test strains of Candida fungi: C. albicans ATCC 885/653, C. parapsilosis 488/10, С. Read more
On the model of burn trauma of degree II in rats the effectiveness of “Bioflorin” ointment containing a thick oak bark extract and the essential oil of coriander has been studied. The known reparative ointment of the natural origin “Algofin” Read more
